Microfluidic arrangements are created in a dish by simple reshaping of two immiscible fluids, which additionally are bio-inert, and freely permeable to the vital gases, oxygen and carbon dioxide. This is demonstrated using workflows involving cell cloning, the selection of one clone from others in a dish, drug treatments, and wound healing.
Cristian Soitu and Cyril Deroy are the two engineering students developing this technology, spending much of their time in the Department of Pathology. Cristian (supervised by Prof Walsh and Prof Alfonso Castrejón-Pita) said ‘this multi-disciplinary research enables biologists to use their familiar materials and approaches in simple ways that saves them money, reduces waste, and speeds their research’; Cyril (supervised by Prof Walsh) added ‘we hope biologists will now embrace this technology because everything about it is so familiar to them.’
Both students are funded by iotaSciences Ltd, a company that was spun out from the University to exploit this technology.