A fluid-shaping technology developed by engineers and scientists from the Oxford Thermofluids Institute, Department of Engineering Science and The Sir William Dunn School of Pathology resulted in the spin out company iotaSciences.

iotaSciences received the New Product Award at SLAS2018 in recognition of their innovative and portable benchtop single-cell instrument.

The isoCell, which was showcased publicly for the first time at the event, utilizes proprietary fluid-shaping technology, originally developed at the University of Oxford, to create small-scale liquid chambers (microGRIDS) and deposits single cells into them. The system overcomes a main obstacle in assuring the monoclonality of cells by providing excellent optical clarity on any microscope, providing a very cost-effective solution in workflows requiring single cells.

A microgrid side view

The system will support a breadth of academic and industrial applications – accelerating the research and discovery of next-generation therapeutics, including CRISPR-Cas9 genome editing, production of monoclonal antibodies and protein therapeutics, the establishment of novel cellular disease models and others.

The SLAS2018 meeting held in San Diego (US) represented the flagship annual conference of the society and was attended by a record-breaking 6,600 delegates – bringing together leading researchers and technologists, engineers and key opinion leaders covering diverse areas of technology and innovation. More than 300 companies exhibited their latest technologies and trends at this impactful event, 50 of which entered the competition for the SLAS2018 New Product Awards. The selection criteria for the awards were ‘innovation, market opportunity, proof-of-concept and originality’.